Week 12 Games
| Date (Day) | Home Team | Score | Score | Away Team | Location | |||||
| Dec 12, 1959 (Sat) | Los Angeles Rams | 26 | 45 | Baltimore Colts | Los Angeles Memorial Coliseum | standings | ||||
| Dec 13, 1959 (Sun) | Philadelphia Eagles | 21 | 28 | Cleveland Browns | Franklin Field | standings | ||||
| Dec 13, 1959 (Sun) | Pittsburgh Steelers | 35 | 20 | Chicago Cardinals | Forbes Field | standings | ||||
| Dec 13, 1959 (Sun) | Chicago Bears | 25 | 14 | Detroit Lions | Wrigley Field | standings | ||||
| Dec 13, 1959 (Sun) | San Francisco 49ers | 14 | 36 | Green Bay Packers | Kezar Stadium | standings | ||||
| Dec 13, 1959 (Sun) | Washington Redskins | 10 | 24 | New York Giants | Griffith Stadium | standings |