Week 10 Games
| Date (Day) | Home Team | Score | Score | Away Team | Location | |||||
| Nov 26, 1959 (Thu) | Detroit Lions | 17 | 24 | Green Bay Packers | Briggs Stadium | standings | ||||
| Nov 29, 1959 (Sun) | New York Giants | 45 | 14 | Washington Redskins | Yankee Stadium | standings | ||||
| Nov 29, 1959 (Sun) | Cleveland Browns | 20 | 21 | San Francisco 49ers | Cleveland Municipal Stadium | standings | ||||
| Nov 29, 1959 (Sun) | Baltimore Colts | 35 | 21 | Los Angeles Rams | Memorial Stadium | standings | ||||
| Nov 29, 1959 (Sun) | Pittsburgh Steelers | 31 | 0 | Philadelphia Eagles | Forbes Field | standings | ||||
| Nov 29, 1959 (Sun) | Chicago Cardinals | 7 | 31 | Chicago Bears | Soldier Field | standings |