| Players Picked at #66 | ||||||||||
| Season | Pick # | Team | Name | Position | College | |||||
| 2025 | 66 | Kansas City Chiefs | Ashton Gillotte | EDGE | Louisville | |||||
| 2024 | 66 | Arizona Cardinals | Trey Benson | RB | Florida State | |||||
| 2023 | 66 | Philadelphia Eagles | Sydney Brown | S | Illinois | |||||
| 2022 | 66 | Minnesota Vikings | Brian Asamoah | LB | Oklahoma | |||||
| 2021 | 66 | Minnesota Vikings | Kellen Mond | QB | Texas A&M | |||||
| 2020 | 66 | Washington Football Team | Antonio Gibson | WR | Memphis | |||||
| 2019 | 66 | Pittsburgh Steelers | Diontae Johnson | WR | Toledo | |||||
| 2018 | 66 | New York Giants | Lorenzo Carter | LB | Georgia | |||||
| 2017 | 66 | San Francisco 49ers | Ahkello Witherspoon | CB | Colorado | |||||
| 2016 | 66 | San Diego Chargers | Max Tuerk | C | USC | |||||
| 2015 | 66 | Tennessee Titans | Jeremiah Poutasi | G | Utah | |||||
| 2014 | 66 | Washington Redskins | Morgan Moses | T | Virginia | |||||
| 2013 | 66 | Oakland Raiders | Sio Moore | LB | Connecticut | |||||
| 2012 | 66 | Minnesota Vikings | Josh Robinson | CB | Central Florida | |||||
| 2011 | 66 | Cincinnati Bengals | Dontay Moch | LB | Nevada-Reno | |||||
| 2010 | 66 | Detroit Lions | Amari Spievey | CB | Iowa | |||||
| 2009 | 66 | St Louis Rams | Bradley Fletcher | CB | Iowa | |||||
| 2008 | 66 | Miami Dolphins | Kendall Langford | DE | Hampton | |||||
| 2007 | 66 | New Orleans Saints | Usama Young | CB | Kent State | |||||
| 2006 | 66 | Houston Texans | Eric Winston | T | Miami (FL) | |||||
| 2005 | 66 | St Louis Rams | O.J. Atogwe | S | Stanford | |||||
| 2004 | 66 | San Diego Chargers | Nick Hardwick | C | Purdue | |||||
| 2003 | 66 | Detroit Lions | Cory Redding | DT | Texas | |||||
| 2002 | 66 | Houston Texans | Fred Weary | G | Tennessee | |||||
| 2001 | 66 | Cincinnati Bengals | Sean Brewer | TE | San Jose State | |||||
| 2000 | 66 | Cincinnati Bengals | Ron Dugans | WR | Florida State | |||||
| 1999 | 66 | Chicago Bears | Rex Tucker | T | Texas A&M | |||||
| 1998 | 66 | Pittsburgh Steelers | Chris Conrad | T | Fresno State | |||||
| 1997 | 66 | Tampa Bay Buccaneers | Ronde Barber | CB | Virginia | HOF - 2023 | ||||
| 1996 | 66 | New York Giants | Roman Oben | T | Louisville | |||||
| 1995 | 66 | Green Bay Packers | William Henderson | RB | North Carolina | |||||
| 1994 | 66 | Cincinnati Bengals | Jeff Cothran | FB | Ohio State | |||||
| 1993 | 66 | New York Giants | Marcus Buckley | LB | Texas A&M | |||||
| 1992 | 66 | Seattle Seahawks | Bob Spitulski | LB | Central Florida | |||||
| 1991 | 66 | Tampa Bay Buccaneers | Lawrence Dawsey | WR | Florida State | |||||
| 1990 | 66 | Miami Dolphins | Alfred Oglesby | NT | Houston | |||||
| 1989 | 66 | Buffalo Bills | Don Beebe | WR | Chadron State | |||||
| 1989 | 66 | Washington Redskins | Tracy Rocker | DT | Auburn | |||||
| 1988 | 66 | Washington Redskins | Mike Oliphant | RB | Puget Sound | |||||
| 1987 | 66 | Pittsburgh Steelers | Charles Lockett | WR | Long Beach State | |||||
| 1986 | 66 | San Diego Chargers | Terry Unrein | DE | Colorado State | |||||
| 1985 | 66 | Minnesota Vikings | Tim Long | T | Memphis | |||||
| 1984 | 66 | Indianapolis Colts | Chris Scott | DT | Purdue | |||||
| 1983 | 66 | New Orleans Saints | Cliff Austin | RB | Clemson | |||||
| 1982 | 66 | New Orleans Saints | Eugene Goodlow | WR | Kansas State | |||||
| 1981 | 66 | Los Angeles Rams | Robert Cobb | DE | Arizona | |||||
| 1980 | 66 | Kansas City Chiefs | James Hadnot | RB | Texas Tech | |||||
| 1979 | 66 | Chicago Bears | Willie McClendon | RB | Georgia | |||||
| 1978 | 66 | Philadelphia Eagles | Reggie Wilkes | LB | Georgia Tech | |||||
| 1977 | 66 | Houston Oilers | Tim Wilson | RB | Maryland | |||||
| 1976 | 66 | Chicago Bears | Brian Baschnagel | WR | Ohio State | |||||
| 1975 | 66 | New England Patriots | Pete Cusick | DT | Ohio State | |||||
| 1974 | 66 | Kansas City Chiefs | David Jaynes | QB | Kansas | |||||
| 1973 | 66 | New Orleans Saints | Pete Van Valkenburg | RB | BYU | |||||
| 1972 | 66 | New York Jets | Gary Hammond | WR | SMU | |||||
| 1971 | 66 | Cleveland Browns | Paul Staroba | WR | Michigan | |||||
| 1970 | 66 | Dallas Cowboys | Charlie Waters | S | Clemson | |||||
| 1969 | 66 | Chicago Bears | Ross Montgomery | RB | TCU | |||||
| 1968 | 66 | Cleveland Browns | Reece Morrison | RB | Texas State | |||||
| 1967 | 66 | New York Jets | Dennis Randall | DE | Oklahoma State | |||||
| 1966 | 66 | Los Angeles Rams | Diron Talbert | T | Texas | |||||
| 1965 | 66 | Green Bay Packers | Doug Goodwin | RB | Maryland-Eastern Shore | |||||
| 1964 | 66 | Pittsburgh Steelers | T.W. Alley | T | William & Mary | |||||
| 1963 | 66 | San Francisco 49ers | Gary Moeller | G | Ohio State | |||||
| 1962 | 66 | Detroit Lions | Dan Birdwell | C | Houston | |||||
| 1961 | 66 | Detroit Lions | Earl Faison | E | Indiana | |||||
| 1960 | 66 | Los Angeles Rams | Don Ellersick | E | Washington State | |||||
| 1959 | 66 | San Francisco 49ers | Tony Bavaro | T | Holy Cross | |||||
| 1958 | 66 | Washington Redskins | Dick Lynch | B | Notre Dame | |||||
| 1957 | 66 | Pittsburgh Steelers | George Volkert | B | Georgia Tech | |||||
| 1956 | 66 | Chicago Cardinals | Charlie Dupre | B | Baylor | |||||
| 1955 | 66 | Pittsburgh Steelers | Lem Harkey | B | Emporia State | |||||
| 1954 | 66 | Chicago Bears | John Hudson | G | Rice | |||||
| 1953 | 66 | Pittsburgh Steelers | Tom Barton | G | Clemson | |||||
| 1952 | 66 | Los Angeles Rams | Duane Putnam | G | Pacific | |||||
| 1951 | 66 | Chicago Cardinals | Ed Jasonek | B | Furman | |||||
| 1950 | 66 | Philadelphia Eagles | Mike Kaysserian | B | Detroit Mercy | |||||
| 1949 | 66 | New York Giants | Frank LoVuolo | E | St. Bonaventure | |||||
| 1948 | 66 | New York Giants | Dick Ottele | B | Washington | |||||
| 1947 | 66 | Detroit Lions | Kale Alexander | T | South Carolina | |||||
| 1946 | 66 | Green Bay Packers | Bert Cole | T | Oklahoma State | |||||
| 1945 | 66 | Pittsburgh Steelers | Tom Hughes | T | Missouri | |||||
| 1944 | 66 | Chicago Cardinals | John Cochran | B | Wake Forest | |||||
| 1943 | 66 | New York Giants | Larry Visnic | G | St. Benedictine | |||||
| 1942 | 66 | Washington Redskins | George Peters | B | Oregon State | |||||
| 1941 | 66 | Green Bay Packers | Bill Kuusisto | G | Wisconsin | |||||
| 1940 | 66 | Detroit Lions | Bill Tranavitch | B | Rutgers | |||||
| 1939 | 66 | Chicago Bears | Bob Dannies | C | Pittsburgh | |||||
| 1938 | 66 | Detroit Lions | Dick Nardi | HB | Ohio State | |||||
| 1937 | 66 | Washington Redskins | Rolla Holland | G | Kansas State | |||||
| 1936 | 66 | Pittsburgh Pirates | Ed Karpowich | T | Catholic University | |||||
