| Players Picked at #150 | ||||||||||
| Season | Pick # | Team | Name | Position | College | |||||
| 2025 | 150 | Miami Dolphins | Jason Marshall Jr. | CB | Florida | |||||
| 2024 | 150 | New Orleans Saints | Spencer Rattler | QB | South Carolina | |||||
| 2023 | 150 | Buffalo Bills | Justin Shorter | WR | Florida | |||||
| 2022 | 150 | Houston Texans | Thomas Booker | DT | Stanford | |||||
| 2021 | 150 | Philadelphia Eagles | Kenneth Gainwell | RB | Memphis | |||||
| 2020 | 150 | New York Giants | Shane Lemieux | G | Oregon | |||||
| 2019 | 150 | Green Bay Packers | Kingsley Keke | DT | Texas A&M | |||||
| 2018 | 150 | Cleveland Browns | Genard Avery | LB | Memphis | |||||
| 2017 | 150 | New York Jets | Jordan Leggett | TE | Clemson | |||||
| 2016 | 150 | Chicago Bears | Jordan Howard | RB | Indiana | |||||
| 2015 | 150 | Miami Dolphins | Cedric Thompson | S | Minnesota | |||||
| 2014 | 150 | San Francisco 49ers | Aaron Lynch | DE | South Florida | |||||
| 2013 | 150 | Pittsburgh Steelers | Terry Hawthorne | CB | Illinois | |||||
| 2012 | 150 | St Louis Rams | Rokevious Watkins | G | South Carolina | |||||
| 2011 | 150 | Cleveland Browns | Jason Pinkston | T | Pittsburgh | |||||
| 2010 | 150 | New England Patriots | Zoltan Mesko | P | Michigan | |||||
| 2009 | 150 | Minnesota Vikings | Jasper Brinkley | LB | South Carolina | |||||
| 2008 | 150 | Green Bay Packers | Breno Giacomini | T | Louisville | |||||
| 2007 | 150 | Jacksonville Jaguars | Josh Gattis | S | Wake Forest | |||||
| 2006 | 150 | New York Jets | Jason Pociask | TE | Wisconsin | |||||
| 2005 | 150 | Tennessee Titans | Daniel Loper | T | Texas Tech | |||||
| 2004 | 150 | Jacksonville Jaguars | Chris Thompson | CB | Nicholls State | |||||
| 2003 | 150 | New York Jets | Matt Walters | DE | Miami (FL) | |||||
| 2002 | 150 | New Orleans Saints | Mel Mitchell | S | Western Kentucky | |||||
| 2001 | 150 | Kansas City Chiefs | Derrick Blaylock | RB | Stephen F. Austin | |||||
| 2000 | 150 | San Francisco 49ers | John Milem | DE | Lenoir-Rhyne | |||||
| 1999 | 150 | Tampa Bay Buccaneers | John McLaughlin | DE | California | |||||
| 1998 | 150 | Green Bay Packers | Corey Bradford | WR | Jackson State | |||||
| 1997 | 150 | Indianapolis Colts | Nate Jacquet | WR | San Diego State | |||||
| 1996 | 150 | Miami Dolphins | Shane Burton | DT | Tennessee | |||||
| 1995 | 150 | Arizona Cardinals | Cedric Davis | CB | Tennessee State | |||||
| 1994 | 150 | San Diego Chargers | Darren Krein | DE | Miami | |||||
| 1993 | 150 | New York Giants | Scott Davis | G | Iowa | |||||
| 1992 | 150 | Seattle Seahawks | Michael Bates | WR | Arizona | |||||
| 1991 | 150 | San Diego Chargers | Jimmy Laister | T | Oregon Tech | |||||
| 1990 | 150 | Cincinnati Bengals | Don Odegard | CB | UNLV | |||||
| 1989 | 150 | Phoenix Cardinals | Jay Taylor | DB | San Jose State | |||||
| 1988 | 150 | Buffalo Bills | Dan Murray | OLB | East Stroudsburg (PA) | |||||
| 1987 | 150 | Pittsburgh Steelers | Greg Lloyd | LB | Fort Valley State | |||||
| 1986 | 150 | Dallas Cowboys | Stan Gelbaugh | QB | Maryland | |||||
| 1985 | 150 | San Diego Chargers | Terry Lewis | DB | Michigan State | |||||
| 1984 | 150 | Cincinnati Bengals | Don Kern | TE | Arizona State | |||||
| 1983 | 150 | Seattle Seahawks | Reginald Gipson | RB | Alabama A&M | |||||
| 1982 | 150 | St. Louis Cardinals | Craig Shaffer | LB | Indiana State | |||||
| 1981 | 150 | Chicago Bears | Reuben Henderson | CB | San Diego State | |||||
| 1980 | 150 | New Orleans Saints | Lester Boyd | LB | Kentucky | |||||
| 1979 | 150 | Baltimore Colts | Jim Moore | T | Ohio State | |||||
| 1978 | 150 | Detroit Lions | Dwight Hicks | S | Michigan | |||||
| 1977 | 150 | Kansas City Chiefs | Rick Burleson | DE | Texas | |||||
| 1976 | 150 | Los Angeles Rams | Ken Bordelon | DE | LSU | |||||
| 1975 | 150 | Cleveland Browns | Charles Miller | DB | West Virginia | |||||
| 1974 | 150 | Pittsburgh Steelers | Rick Druschel | G | North Carolina State | |||||
| 1973 | 150 | Cleveland Browns | Van Green | DB | Shaw | |||||
| 1972 | 150 | New Orleans Saints | Curt Watson | RB | Tennessee | |||||
| 1971 | 150 | Detroit Lions | Frank Harris | QB | Boston College | |||||
| 1970 | 150 | New York Jets | Terry Stewart | DB | Arkansas | |||||
| 1969 | 150 | Cleveland Browns | Joe Righetti | DT | Waynesburg | |||||
| 1968 | 150 | Philadelphia Eagles | Thurman Randle | T | Texas-El Paso | |||||
| 1967 | 150 | St. Louis Cardinals | Mike Campbell | RB | Lenoir-Rhyne | |||||
| 1966 | 150 | Detroit Lions | Tom Brigham | DE | Wisconsin | |||||
| 1965 | 150 | Green Bay Packers | Jim Weatherwax | DE | West Texas A&M | |||||
| 1964 | 150 | Pittsburgh Steelers | Bob Soleau | G | William & Mary | |||||
| 1963 | 150 | Chicago Bears | James Tullis | DB | Florida A&M | |||||
| 1962 | 150 | Detroit Lions | Karl Anderson | T | Bowling Green | |||||
| 1961 | 150 | Detroit Lions | Larry Vargo | E | Detroit Mercy | |||||
| 1960 | 150 | Pittsburgh Steelers | Joe Womack | RB | California State-L.A. | |||||
| 1959 | 150 | San Francisco 49ers | Bill Lopasky | G | West Virginia | |||||
| 1958 | 150 | Washington Redskins | Ken Ford | QB | Hardin-Simmons | |||||
| 1957 | 150 | Cleveland Browns | Jerry Sansom | E | Auburn | |||||
| 1956 | 150 | Philadelphia Eagles | James Sides | B | Texas Tech | |||||
| 1955 | 150 | Pittsburgh Steelers | Jim Whitmer | B | Purdue | |||||
| 1954 | 150 | Chicago Bears | Julius Seaholm | G | Texas | |||||
| 1953 | 150 | Chicago Bears | Larry Strickland | C | North Texas | |||||
| 1952 | 150 | Pittsburgh Steelers | Dave Flood | B | Notre Dame | |||||
| 1951 | 150 | Green Bay Packers | Ed Stephens | B | Missouri | |||||
| 1950 | 150 | New York Giants | Ray Wietecha | C | Northwestern | |||||
| 1949 | 150 | Chicago Cardinals | Bob McQuade | B | Xavier | |||||
| 1948 | 150 | Los Angeles Rams | Larry Brink | E | Northern Illinois | |||||
| 1947 | 150 | Chicago Cardinals | Bob Ravensburg | E | Indiana | |||||
| 1946 | 150 | Los Angeles Rams | Larry Bouley | B | Georgia | |||||
| 1945 | 150 | Washington Redskins | Eddie Saenz | B | USC | |||||
| 1944 | 150 | Chicago Bears | Bill Milner | G | Duke | |||||
| 1943 | 150 | Washington Redskins | Joe Day | B | Oregon State | |||||
| 1942 | 150 | Chicago Bears | George Abel | G | Nebraska | |||||
| 1941 | 150 | Washington Redskins | Ken Dow | B | Oregon State | |||||
| 1940 | 150 | New York Giants | Ned Swan | C | Drake | |||||
| 1939 | 150 | New York Giants | Ted Panish | B | Bradley | |||||
